Applied molecular biology Essay Example | Topics and Well Written Essays - 500 words

Applied molecular biology - Essay Example One of the subclasses was germinal-center B-cell-like DLBCL which showed an expression pattern the same as the mature germinal-center B-cells and portended a more favorable prognosis with a 60% five-year survival rate. Besides that, two other DLBCL subclasses, these are, type-3 DLBCL and activated B-cell-like DLBCL, presented much less favorable prognoses with a 35% five-year survival rate. From all these and the researches, it may be possible to determine the patients that might benefit from more aggressive therapies such as chemotherapy regimens or bone marrow transplants when DLBCL is diagnosed. HD DNA microarray studies have highlighted molecular pathways that are important in cancer subclasses. Example, researchers have observed that several genes in the activated B-cell subclass of DLBCL were downstream targets of the NFkB transcription factor. They proved that NFkB activity is higher in this DLBCL subtype thereby suggesting that drugs targeting the NFkB may be effective in the treatment of these tumors. (Cain, 2011) Gene expression profiling of tumor specimens may be useful in the pre-selection of patients who may benefit from drug treatment. It can also be used in examining gene expression profiles of cancers following chemotherapy so as to determine whether the tumors are responding to treatment. In this method, detailed patient-specific molecular information would be used to predict an effective therapy. (Schwab,

Jerusalem Movie Review Example | Topics and Well Written Essays - 1750 words - 1

Jerusalem - Movie Review Example the Jews believe that the Western Wall is the holiest site on Earth and they hold the city of Jerusalem dear to their heart and would do anything to protect the city against invaders. The video also explains the relevance of Jerusalem to the Muslims with historical evidence on the exploits of Muhammad (the central figure in Islam) in the city as he was believed to have ascended to heaven from the Dome of the Rock. Thus, it could be argued that the video provided a balanced view on all three Abrahamic faiths (Jennings). Jennings presented the three principal perspectives of Jerusalem. He critically analyzed the perspectives of the Jews, Christians and Muslims on the significance of Jerusalem. Peter Jennings takes his time out to get the different views about the story of Abraham, who the Muslims and the Jews take as their ancestor. The opinion of the Christians about Abraham was also sought by Jennings as the Christians believe that he was a man of faith. Jennings interviewed a Jewish couple, Muslim family and a Catholic priest to hear what they had to say about the significance of Jerusalem to their individual religions. Jennings learnt the actual Way of the Cross (pictures that represent the passage of Jesus Christ to Calvary) from the Catholic priest; he also learnt of the roots of the Muslims that spanned eight centuries. The Jewish couple helped Jennings to excavate a primordial Jewish home under their home in order to establish some truth about the history of their religion. The video shows that Christians all over the world come to Jerusalem for pilgrimage yearly, while Muslims also visit the Temple Mount to honor God and remember the deeds of the ‘holy prophet’ Muhammad in the city. B. Religion plays a very important role in the Middle East. Countries relate with themselves based on their religious affiliations. Islam is the predominant religion of the people in the Middle East. In these Islamic countries, one must be a Muslim in order to hold a

Gabriel Oak Essay Example for Free

Gabriel Oak Essay How do you account for Bathshebas choice of husband when she could have married either Gabriel Oak or William Boldwood? Bathsheba married Troy because he offered her an exciting lifestyle full of lust and venture. On the other hand, she rejected Oak and Boldwood because they offered her a secluded life of security in a traditional living. The book was written in episodes for a Victorian magazine. People of the times expected a happy ending, Hardy wanted to please his readers but incorporate the hardships of life at the same time. He structures the book so that Bathsheba is dragged through her misfortunes and undeserving men, whilst throughout the duration of the book the readers still feel that Bathsheba should ultimately be in wedlock with Gabriel. This is clever of Hardy because despite the tragedy of death there is love to sooth the mind. In the time in which the book was written, men and women were only allowed to be together if the Lady has a chaperone, this was the socially accepted thing. Therefore, if a man got a woman pregnant it would be unacceptable of him not to marry her. Hardy felt that women were treated badly in the eyes of society. He felt that when women were married, the behaviour and character of the man they were married to shaped their lifestyles. In the Victorian period, women who did not marry found it very hard in society. They depended on their own financial security and were looked down upon because they were not married. He felt that women were swept up in the excitement of new love and lust and when they were married without true love, they would regret the mistake for the rest of their lives. Scarlet fever was the nickname for the obsession that the local girls had for the officers in the regiment who settled in their town, their scarlet coats being the basis of this nickname. Hardys Aunt Martha was in fact one of the victims of Scarlet fever. She ran off with a cavalryman, John Breton Sharpe. This may have been his inspiration for the character of Troy: attractive and exciting on the outside but fickle and insecure on the inside. When Troy and Bathsheba first meet, in chapter 24, the corner of her dress gets caught in his spur and as they struggle to untangle themselves he is very bold and brazen to her. He makes flirtatious comments that appeal to her vanity, Thank you for the sight of such a beautiful face! Although Bathsheba is flattered by his compliments, she does not know how to handle his over confident behaviour and is eager to get away because she is alone with a single man in the dark; with a reputation to uphold. She suggests that he is only entangling her dress further so that he can keep her there, O, tis shameful of you; you have been making it worse on purpose to keep me here you have! After he finally looses the dress from his spurs, he is even as daring as to make a reference to marriage, I wish it had been the knot of knots, which theres no untying! This makes her even more desperate to get away and on her retreat he makes another remark that makes him ever more attractive to Bathshebas vane nature, Ah, Beauty; good-bye! When Bathsheba, returns home, she learns from Liddy that Troy is high-born and very intelligent; He was brought up so well, and sent to Casterbridge grammar school for years and years. , Hes a doctors son by name and an earls son by nature Nobility of blood will outshine even in the ranks and files. Already, Bathsheba is attracted to Troys Redcoat exterior and his bold flirtatious manner. At their next meeting, Troy succeeds in dazzling Bathsheba with his witty remarks about men and their love for women; Probably some one man on an average falls in love with each ordinary woman such a woman as you a hundred men will always covet and once again he showers her with compliments; I would rather have curses from you than kisses from any other woman. Troy finally achieves to bewitch Bathsheba in chapter twenty-eight. When Bathsheba and Troy meet in the ferns, Troy impresses her with his skill with a sword. He tells her that the sword he is using is blunt when really it is razor sharp; No edge! This sword will shave like a razor. Troy takes the liberty of slicing a caterpillar that had settled on Bathshebas chest and cutting a stray lock of her hair. At this point, Hardy may have been influenced by the poem written by Alexander Pope called The Rape of the Lock. In this poem, Pope writes about a man named Lord Fermor, who cuts a lock of hair from the Lady Arabella except for the loss of your hair, which I shall always name in reverence. This is a symbol of sexual achievement. Later on in the book, we found out that Troy is also in the possession of a lock of Fanny Robins hair, so this would lead us to suspect that Troy regards this as trophy collecting or personal reminders of all the women he has seduced. Troy is the first man to kiss Bathsheba and this has a definite impact on her. The minutes interval had brought the blood beating into her face And enlarged emotion to a compass which quite swamped thought He had kissed her. After this event, Troy travels to Bath and Bathsheba follows him for many reasons. One of these reasons is that when she is on the road one afternoon, she meets Farmer Boldwood. He is obsessively in love with her and shouts at her, threatening Troy and cursing his name; Ill punish him be he soldier or no if he were one hundred men Id hose whip him. Bathsheba is very frightened for Troy and thinks long and hard about what to do in her trivial situation. She decides to go to Bath. She will warn Troy not to come back and to see him one last time before she end their relationship; Her plan was now to drive to Bath during the night, see Sergeant Troy in the morning before he set out to come to her, bid him farewell and dismiss him. Although this seemed like the best thing to do to save anyone from getting hurt, Bathsheba talks with Gabriel about the reasons for her ultimate commitment to Troy; I went to Bath that night with the full intention of breaking off my engagement to Mr. Troy Well I was alone in a strange city, and the horse was lame I saw, at last, when it was too late that scandal might seize hold of me for meeting alone him in that way. I was coming away when he suddenly said he had that day seen a woman more beautiful than I, and that his constancy could not be counted on unless I at once became his And then between jealousy and distraction I married him. Here we see one of the main reasons that Bathsheba married Troy he made her desperately jealous by manipulating her emotions.

The Products Of Herbal Essences Marketing Essay

The Products Of Herbal Essences Marketing Essay Herbal Essences is a brand of hair product founded in 1971 by Clairol. In 2002, Procter and Gamble acquired Herbal Essences from Clairol, Inc. Herbal Essences is a global brand of hair-care products that distribute various different Shampoo, Conditioner, Hair Coloring, Mousse, Hairspray, and Gel products (Procter Gamble, 2012, p. 3). Procter and Gamble entered as a hair colorant and renovated the product of Herbal Essences (Matusow, 2008). In this section we will analyze the target market strategies, which Procter and Gamble used to help their product Herbal Essences grow more than 40 percent in sales globally (Procter Gamble, 2007, p. 12). According to McGreog (2008), since Procter and Gamble acquired Herbal Essences their main marketing objective was to change their product and to revive their failing brand within the shampoo industry. Hence, the company wanted to market towards a more youthful audience. The brand was originally focused on women who wanted natural hair care products. It dealt with ingredients such as herbal and organic aspect of the product. Procter and Gamble wanted to reposition their hair products by creating a fun and youthful appeal while having the natural ingredients. Procter and Gamble did this so they do not lose their brand loyalists. Herbal Essences target market consists of Generation Y female users ranging from the age of 14-30 (McGregor, 2008). Herbal Essences target markets are individuals who are going to school, entering college, and young moms. Consumers of Herbal Essencess products share more than a common hair-care product, they share common lifestyles. In order to understand the appeal of their products, Herbal Essences continues to research their cultural and social environment. They do this by learning more about the consumers psychographics and behavioral characteristics. The goal in doing so is to sell more hair products by understanding the changing wants and the needs of the market segment. The needs of this market segment According to MediaPost (2008), in recent efforts to better understand and attract the youthful audience towards Herbal Essences, Procter Gamble and the Beauty Business Chief, Susan Arnold had an idea to re-invent their products by completely re-branding Herbal Essences. In order to rebrand themselves they conducted their own research such as consumer surveys, market research and observing buying patterns of younger consumers. She took on the task of finding a way to build up the failing brand with a small group of people from research and development, marketing, and design. The small team worked together with branding agency Libby Perszyk Kathman (LPK) to target the market of Generation Y females (MediaPost, 2008). As Lukovitz (2007) states in her article Herbal Essence Snags 2007 Rebrand 100 Global Award the team instantly started on 18 months of extensive consumer research. During the time the team emerged in May 2006 with a new target market audience tailored towards the spontaneous, optimistic, altruistic, experiential Generation Y (Lukovitz, 2007). Herbal Essences changed the whole product from scratch which they referred to as the from-scratch strategy which included a new logo, adding several catchy new product names, and adding new packaging. Herbal Essences research discovered that women like to buy hair care products within the same brand. The packaging emphasizes the shape, the new shampoo and conditioner bottles where designed to fit together on the shelf, encouraging the youthful audience to buy the product as a whole and driving up sales (Lukovitz, 2007). In order for Herbal Essences to communicate their product to their new target market, they have used an innovative way to reflect their product upon the youthful generation. Herbal Essences uses this technique consistently throughout their product packaging and promotions. For example, the names of their products such as Hello Hydration, Drama Clean, and Tousle Me Softly (Herbal Essences, 2012). The name of these products reflects the tone and personality of the youthful audience which effectively appeals to their target market. Their target market likes to be aware of the latest trends in hairstyles and looks that could be obtained by using their products. Their target market wants a brand that focuses on their needs and is funky as them; a product which has an emotional connection, and makes them feel like the product is a part of their lifestyle. This market strategy also play a role into targeting the older part of the demographic, towards young mothers around the age of 30 who may look for hair care products for their daughters. They would be prone to buy the product since it gives a youthful and a modern vibe unlike other hair care product competitors. Herbal Essences indirectly cleverly uses the youthful appeal towards the older demographics that could also purchase their product, because they are tempted to feel younger (Lukovitz, 2007). Herbal Essences revolutionized the way companies target their market. It moved from a failing brand into a successful brand. The strategies they applied into targeting their market changes the way companies and their products speak to their consumers, appears to their customers, and how they might even position their products on the shelf to compete with their competitors (McGregor, 2008). Herbal Essences hair-care products stand out because it has been designed and formulated specifically for their target market needs. With the products of Herbal Essences, their target market can match their unique personality with their products.

The Female on Trial :: Gender Studies Research papers

The Female on Trial The theme of the first semester of my senior year at Bryn Mawr College, although I have lacked any gender coursework in my first three years of semesters, unexpectedly heavily involves the collision of the science, literature, and politics of gender. As my most last minute, haphazard schedule of any semester ever, on the next to last day of the shopping week period, I found myself adding two gender studies classes to my schedule. One entitled Advanced Topics in Developmental Psychology for my Psychology minor, and the other entitled, Interdisciplinary Perspectives of Sex and Gender. Both classes, although very different in their methodology - (one placing a profound importance on precision, cautious and careful experiment design, and the other on "stories" both individual and collective, and their relation to society) - hoped to find the "real" gender problems, look at them with the attention they deserve, and encourage some kind of dialogue for change. Gender Development, as a psychology class, was focused on the role of psychology in reporting only what can be proven, or statistically "significant." It took the stance that science, although slow, has the advantage of facts, which my professor insisted are key for social recognition of a problem which can be sited and lead to broad social change. My other class was in Bryn Mawr and Haverford's shared Feminist and Gender Studies department, although it spent a few classes dedicated to looking at gender from a biological perspective, in general, has looked less at the science, and more at the story or groups of stories that intellectuals tell about their own personal experience, as well as their observations of the larger societal picture concerning gender and sexuality. The class also encouraged intellectual discussions like we were participating in class about these topics and believed the dialogues were key for opening an awareness that might lead to social improvement. I have con tinually struggled with the scientific and intellectual representations of gender development and stigmatization, especially regarding the role of socialization (by "socialization" I mean the stereotypes and stigmas placed on individuals by society based on their sex, sexuality, or gender). How do I define my own experience, do either of these classes tell a better picture for me and my story, or for society, do either provide a better or at least more useful story? My thinking about these questions came to a head when in my final Advanced Topics in Developmental Psychology class, for the first time the professor had not asked the class to read a cluster of psychological studies.

Oedipal and Electra Complexes Essay example -- Sexuality Heroine Freud

Oedipal and Electra Complexes In Rebecca female sexuality is explored through the heroine’s symbolic development of a negative Oedipal complex followed by an Electra complex. Although avoidance of incest was believed by Freud to be the impetus for normal sexual development, the film explores the abnormal outcome of a negative Oedipal/Electra complex, i.e. replacement of the mother by the daughter as the father’s heterosexual love interest. The heroine is torn between her desire to merge with Rebecca and to separate from her due to this combination of negative Oedipal and Electra complexes. The key difference between these two complexes underlies the heroine’s development. The difference between a negative Oedipal and Electra complex is not subtle. A negative Oedipal complex involves love for the mother in the form of Freud’s â€Å"bisexual attraction†. The girl will desire and identify with her, wishing to emulate her. An Electra complex is defined by the girl’s imagined rivalry between mother and daughter for the father’s love. For Freud the heterosexual development of little girls is more difficult to explain compared to that of little boys because the girl must change the object of her love from woman to man. Initially the girl has a negative Oedipal complex until some catalytic occurrence shifts her into an Electra complex marked by dislike of the mother and rivalry. In a normal Freudian non-incestuous relationship the girl will transfer love of the father to other men and will not stop loving the mother entirely. In an incestuous relationship the girl will eliminate the threat of the mother, take her place, and engage in a sexual relationship with the father. Avoiding this, Freud believes, drives the female sexual development. Embracing this, Hitchcock displays, drives the unheimlich development of Rebecca. Symbolically in the film, the main characters take on the roles of key players in Freud’s development strategies. The lovely heroine is clearly the girl, very young relative to Maxim and for the first half of the film innocent, weak, and small. She is made smaller by the overpowering presence of Rebecca, who for her typifies the perfect female. Maxim is clearly the father figure due to his age relative to the heroine and his relationship with her. His comments about her being a child, his desire for her never to grow up or wear ... ...e destruction of Mandalay and the death of Danvers, her last true worshiper. The last scene shows Maxim and the heroine embracing, insinuating that they go on to a heterosexual, symbolically incestuous relationship that is not overshadowed by Rebecca. In short the heroine’s development in the film from a naive, weak little girl into a powerful, knowledgeable wife is mirrored by this symbolic transition from a negative Oedipal stage to an Electra stage to a father-daughter incestuous relationship. The heroine’s actions are not given explicit justification in the film, but the typical behavior of Freud’s proverbial girl matches her behavior perfectly. The heroine tries to become like the woman who she believes Maxim loves, fails, and tries then to compete with her. The twist on the Oedipal/Electra complex comes about when the girl’s feminine rivalry turns to aligned opposition with the father against the mother leading to an incestuous relationship, precisely the outcome Freud’s theory sought to avoid. Because the film’s development of the heroine diverges from normal sexual development in this way, Rebecca’s development attains Hitchcock’s sought after unheimlich effect.

Accumulated Change vs. Definite Integral

Martyna Wiacek MTH 116 C- Applied Calculus 11/6/2012 Chapter 5 Writing Assignment There is a correlation between area, accumulated change, and the definite integral that we have focused on throughout Chapter 5 in Applied Calculus. When looking at one rate-of-change function, the accumulated change over an interval and the definite integral are equivalent, their values could be positive, negative or zero. However, the area could never be negative because area is always positive by definition. The accumulated change looks at the whole area of the function that is between the graph and the horizontal axis.For instance, if f (x) is a rate-of-change function the area between f (x) and the x-axis represents the accumulated change between x = a and x = b. However, the definite integral puts specific limits into the function and the area of a particular region can be determined. For example, if f (x) is a rate-of-change function it means that: is what you can consider the area. The accumulat ion of change in a certain function can be evaluated by using the area of the region between the rate-of-change curve and the horizontal axis.We also see a similar relationship between the rate-of-change graph and the accumulated graph that we saw in derivatives. A minimum in the accumulated graph is caused by the rate-of-change function crossing over from positive to negative. A maximum in the accumulated graph is a result of the rate-of-change function moving from negative to positive. When there is a maximum or minimum in the rate-of-change graph you get an inflection point in the accumulation graph as well. Also, we see that if the rate-of-change function is negative then the accumulated graph is negative and so the accumulation graph is decreasing.However, when the rate-of-change graph is increasing, it does not affect whether or not the accumulated graph is increasing or decreasing. There are several problems in our book that demonstrate this relationship. A specific example t hat I believe did a good job demonstrating it was: The graph in the figure represents the rate of change of rainfall in Florida during a severe thunderstorm t hours after the rain began falling: Part A: Use a grid to count boxes and estimate the accumulated area from 1 to x for values of x spaced 1 hour apart, starting at 0 and ending at 6.Record the estimates in a table. 0| 0| 1| . 4| 2| . 65| 3| 1| 4| 1. 35| 5| 2| 6| 2. 4| Part B: Sketch the graph of the accumulation function based on the table values: Part C: Write the mathematical notation for the function sketched in part b: Part D: Write a sentence of interpretation for the accumulation form 0 to 6 hours: After 6 hours of rainfall in Florida, the amount of rain should accumulate to an estimate of 2. 4 inches.